Cellular Biologist
topos bioSouth San Francisco, CA
Cellular Biologist
topos bioSouth San Francisco, CA
2 days ago
Industries
Research and Development in Biotechnology (except Nanobiotechnology)Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)Biological Product (except Diagnostic) ManufacturingAbout the role
Topos BioAt Topos Bio, we're pioneering drug discovery for intrinsically disordered proteins—targets that have eluded conventional approaches in neurodegeneration, oncology, and cardiometabolic disease.
We're seeking a cell biologist to develop and execute cell-based assays for validating computational predictions and supporting medicinal chemistry efforts. You'll work at the interface of disease biology, protein biophysics, and drug screening.
What you will do:
Develop and optimize mammalian cell-based assays for disordered protein targetsExecute phenotypic and reporter-based screening campaigns to validate computational hitsCharacterize compound activity and support structure-activity relationship studiesCollaborate with computational scientists to integrate experimental data with modeling workflowsEstablish robust assay protocols and quality control metricsWhat we are looking forStrong foundation in mammalian cell culture and cellular assay developmentExperience with disease-relevant cellular modelsAbility to troubleshoot complex biological systems and optimize experimental protocolsTrack record of productivity and effective collaborationPreferredPhD in cell and molecular biology with focus on disease modelsIndustry experience in drug discovery or biotechExperience with reporter assays and high-throughput screening platformsFamiliarity with oncology, neurodegeneration, or metabolic disease modelsTrack record of developing novel cellular assays or screening approaches
Matching similar jobs
JOB OVERVIEW
Experience level
Senior
Location
South San Francisco, CA
Occupation
Molecular and Cellular Biologists
Industry
Research and Development in Biotechnology (except Nanobiotechnology)
Posted
2 days ago
Tired of running searches?
Rank the roles you'd take once, and matches like these arrive on their own.
CREATE PROFILE