About the role

Scientist - III (Senior)
Location: South San Francisco, CA
Pay Rate: $76.97/hr.
Duration: 6 MonthsJob Description
Execute and troubleshoot molecular interaction studies supporting antibody discovery, hit identification, lead optimization, and candidate selection. Generate and analyze binding affinity, kinetics, avidity, epitope binning, competition, and developability data for antibodies, bispecifics, and other biologics. Operate and optimize molecular interaction platforms including SPR, Carterra, Biacore, BLI, KinExA, and related technologies. Perform protein characterization and quantitative analysis of protein-protein interactions. Design assay plans, establish appropriate controls, and interpret complex interaction data to support discovery decisions. Optimize assay workflows for robustness, throughput, data quality, and turnaround time. Troubleshoot assay and instrument issues and support protocol, analysis template, and workflow development. Document experimental methods, results, data quality assessments, and conclusions in laboratory systems and technical reports. Support data analysis, visualization, and workflow improvements for molecular interaction studies.
Education: Master's degree in Biophysics, Biochemistry, Chemistry, Molecular Biology, Protein Sciences, Biomedical Engineering, or related field with 5+ years of hands-on experience .PhD in a related field preferred with 3+ years of hands-on experience .
Required Skills:
  • Biomolecular interactions
  • Protein characterization
  • Protein-protein interaction analysis
  • Surface Plasmon Resonance (SPR)
Carterra BiacoreBio-Layer Interferometry (BLI) KinExABinding affinity and kinetic analysis Antibody/protein interaction assays Molecular interaction data analysis Assay troubleshooting Quantitative data interpretation
Preferred Skills:
  • Therapeutic antibody discovery
  • Bispecific antibody characterization
  • Epitope binning
  • Competition assays
  • Cell binding characterization
  • Receptor pharmacology
  • Developability assessment
  • Antibody engineering
  • Fc biology
  • Protein structure-function analysis
  • Flow cytometry
  • High-throughput screening
  • Laboratory automation
PythonRSpotfire

Matching similar jobs

JOB OVERVIEW

Salary

$76.97/hr

Experience level

Senior

Location

South San Francisco, CA

Occupation

Molecular and Cellular Biologists

Industry

Research and Development in Biotechnology (except Nanobiotechnology)

Posted

2 days ago

Tired of running searches?

Rank the roles you'd take once, and matches like these arrive on their own.

CREATE PROFILE