Senior Scientist I Discovery Chemistry

Responsibilities: Plan, design and execute multi-step syntheses with optimization and troubleshooting Purify and characterize compounds using standard analytical techniques Collaborate across disciplines and participate in project team meetings Make go/no-go decisions and prioritize research efforts based on data Prepare compounds at various scales (50 mg to 50 g) to support program needs Conduct landscape analysis of competitor compounds and platforms to guide novel scaffold design Track project timelines, provide status updates, and communicate progress/issues Present results in written and oral formats and contribute to internal/external reports Write protocols and SOPs for new discovery efforts Train and mentor entry-level staff Maintain equipment, reagents, and lab environment; troubleshoot issues Maintain lab safety and manage hazardous materials; keep well-organized lab notebooks

Key requirements: Ph.D. in Chemistry (or related field) with 2 years postdoc or 2–5 years industry experience in synthetic organic/medicinal chemistry Experience with modern chromatographic techniques, automated flash chromatography, and analytical methods (NMR, HPLC, LCMS) Ability to independently design synthetic routes and perform multi-step syntheses Strong track record in drug discovery with peer-reviewed publications Excellent laboratory skills and safety awareness Knowledge of modern organic synthesis, purification, and analytical methods, plus medicinal chemistry Experience coordinating project work with timelines and stakeholders Proficiency in Microsoft Office, ChemDraw and SD files Self-motivated and independent Strong interpersonal and communication skills Cross-functional collaboration Multi-step synthesis and route planning Compound purification and characterization Analytical techniques (NMR, HPLC, LCMS)