Pharmacokinetics (PK) Scientist

Employment Type: Full-time, temporary/contract Duration: Approximately 6 months, with potential for extension Location: Remote

Position Overview: The Research Scientist, Pharmacokinetics will provide hands-on pharmacokinetic (PK) support to project representatives across an ocular product portfolio. This role will execute the day-to-day analytical, study-monitoring, literature research, and scientific documentation activities necessary to keep preclinical and clinical PK programs moving forward. The ideal candidate will bring a strong foundation in pharmacokinetic principles, hands-on experience with noncompartmental analysis (NCA), excellent scientific writing skills, and the ability to effectively manage multiple projects and priorities.

Key Responsibilities: Perform noncompartmental pharmacokinetic (PK) and/or toxicokinetic (TK) analyses on preclinical and clinical datasets, including ocular and systemic tissue data. Generate PK parameter tables, concentration-time profiles, summary statistics, and other analytical outputs. Interpret and summarize PK/TK findings for review by project representatives. Assemble, reconcile, and perform quality control of PK datasets prior to analysis. Verify sample accountability, below-limit-of-quantification (BLQ) handling conventions, units, and other critical data elements. Monitor ongoing studies conducted at Contract Research Organizations (CROs) and internal laboratories, identifying and escalating study deviations, data anomalies, and other issues to the responsible project representative. Conduct scientific literature searches related to ocular pharmacokinetics, ADME, and competitor products. Synthesize published literature into concise, decision-ready summaries and data packages. Draft, format, and revise PK study reports, report sections, and PK-related protocol language. Route scientific documentation for peer, data-integrity, and managerial review and incorporate reviewer comments. Provide additional scientific and operational support as project needs and priorities evolve. Scope of the Position This is an individual-contributor role supporting multiple project representatives and concurrent programs. The Research Scientist will work under the direction of a senior PK scientist, using established methods with guidance provided for scientific interpretation. The position will also interact with external contract laboratories and CRO partners under appropriate supervision. Key Relationships Internal Partners: PK project representatives, Bioanalytical, Pharmaceutical Development, and other cross-functional scientific partners. External Partners: Bioanalytical and PK CROs, study directors, and contract laboratories.

Education & Experience: BS/BA in Pharmaceutical Sciences, Pharmacokinetics, Pharmacology, Chemistry, Biology, or a related scientific discipline with a minimum of 3 years of relevant experience, ORMS in a related scientific discipline with a minimum of 2 years of relevant experience. PhD candidates are welcome to apply; a PhD is not required for this position. Prior ophthalmic or topical-route experience is a plus but is not required.

Technical Skills: Working knowledge of pharmacokinetic principles and noncompartmental analysis (NCA).Hands-on experience with Phoenix Win Nonlin or comparable pharmacokinetic analysis software strongly preferred. Proficiency with Microsoft Excel and scientific data handling. Ability to assemble, reconcile, review, and quality-check scientific datasets. Demonstrated scientific and technical writing ability, including preparation of study reports or comparable formal scientific documentation. Experience conducting scientific literature searches using Pub Med, Google Scholar, or similar databases. Experience working with preclinical and/or clinical PK datasets preferred. Experience interacting with CROs or contract laboratories is beneficial.

Key Competencies: Ability to effectively multitask across multiple programs and shifting priorities. Proactive, can-do approach and willingness to step in wherever the team needs support. Strong written and verbal communication skills. Excellent attention to detail and commitment to data quality. Strong organizational and follow-through skills. Ability to collaborate effectively with internal scientific teams and external CRO partners. Comfortable working in a fast-paced, matrixed scientific environment. Compensation Pay rate will be determined based on the candidate's education, directly relevant pharmacokinetics and CRO-related experience, and geographic location.