Medical Director, Clinical Development – MRD Portfolio (Solid Tumors)
laboratory of americaDurham, NC
Medical Director, Clinical Development – MRD Portfolio (Solid Tumors)
laboratory of americaDurham, NC
today
Occupations
Natural Sciences ManagersPhysicians, PathologistsMedical Scientists, Except EpidemiologistsIndustries
Medical LaboratoriesResearch and Development in the Physical, Engineering, and Life SciencesOffices of PhysiciansAbout the role
Overview:
As Medical Director, Clinical Development for the MRD Portfolio, you will shape and execute the clinical strategy for MRD and ctDNA-based technologies across solid tumors. You lead evidence generation to support clinical validity, utility, and adoption, partnering with cross-functional teams to drive integration into routine oncology practice. You will collaborate with external investigators and payers to establish MRD testing as a core component of personalized cancer care. This is a leadership role focused on advancing precision oncology and translating data into real patient impact. Compensation / Benefits Medical, Dental, Vision Life, STD/LTD 401(k) and Employee Stock Purchase Plan PTO / FTO Tuition Reimbursement
Responsibilities:
Lead clinical development for the MRD portfolio across solid tumors, directing evidence generation and product adoption initiatives. Develop and execute strategies for MRD/ctDNA technologies across tumor types and clinical settings. Oversee study design and evidence-generation programs to establish clinical validity, utility, and health economic value. Align internal stakeholders on studies, evidence plans, and product development priorities. Translate emerging data into actionable recommendations for portfolio strategy and indication expansion. Act as the senior clinical SME for MRD technologies across the oncology portfolio. Support investigator-initiated studies, strategic collaborations, and real-world evidence programs. Provide medical leadership for product lifecycle from concept to commercialization and lifecycle management. Define clinical evidence requirements, intended use populations, validation strategies, and adoption priorities. Collaborate with R&D, product, and innovation teams on assay development and biomarker strategies. Evaluate competitive technologies and evolving care standards to inform portfolio priorities. Lead external scientific collaborations and engagement with key opinion leaders and societies. Support medical affairs, education, and scientific communications, including publications and congress activities. Mentor colleagues and provide scientific guidance across project teams and stakeholders.
Key requirements:
Board certification in Medical Oncology. 5+ years post-fellowship clinical experience treating solid tumors. 3+ years oncology clinical development or evidence-generation experience in pharma/biotech/diagnostics/academic settings. 8+ years designing and leading prospective/retrospective clinical studies. 5+ years cross-functional experience with operations, biostatistics, regulatory affairs, medical affairs, market access, or commercialization. 20+ presentations at scientific meetings or to healthcare professionals. Strong understanding of oncology trial methodology, biostatistics, and regulatory requirements. Broad knowledge of solid tumor treatments, biomarkers, and precision oncology approaches. cross-functional collaboration stakeholder alignment scientific communication MRD and ctDNA technologies molecular diagnostics clinical trial design and evidence-generation
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JOB OVERVIEW
Experience level
Manager
Location
Durham, NC
Occupation
Natural Sciences Managers
Industry
Medical Laboratories
Posted
today
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